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Gender Med Rev. 2021 September 20: S2050-0521 (21) 00077-9. doi: 10.1016 / j.sxmr.2021.09.002. Online ahead of print.


INTRODUCTION: COVID-19 infection is expected to be associated with an increased likelihood of erectile dysfunction (ED). Given the high transmissibility of COVID-19, erectile dysfunction can be a worrying consequence for a large part of the population.

OBJECTIVES: (1) to summarize the existing published evidence regarding the impact of COVID-19 on the prevalence, severity, treatment and management of erectile dysfunction; and (2) identify health-related trends in emerging literature and identify gaps in existing research literature and make recommendations for future research needs in the field.

METHODS: A scoping literature search was conducted on April 27, 2021. Preferred reporting items for systematic reviews checklist and expanding meta-analyzes for scoping reviews (preferred reporting items for systematic reviews and meta-analyzes-ScR) was followed. The literature search was performed in PubMed using the terms: COVID-19, erectile, sexual and dysfunction. A total of 693 publications were selected for their relevance. The studies were assessed for their level of evidence based on the study design and the rigor of the methodology.

RESULTS: The evidence that COVID-19 infection causes or has an impact on ED is compelling. Four topics emerged regarding the nature of the association between COVID-19 and ED: (1) the biological impact of COVID-19 infection on ED; (2) the impact of COVID-19 on mental health on ED; (3) the impact of COVID-19 on ED management and access to ED treatment; and (4) health disparities and the impact of COVID-19 on ED. Long-term, well-designed studies are needed to clarify the extent of the impact of COVID-19 on ED. The pandemic has exposed several vulnerabilities within health and social systems around the world.

CONCLUSION: COVID-19 has a particularly harmful impact on the health and erectile function of men through biological mechanisms, mental health and access to health care. As the pandemic subsides, strategies to identify long-term effects and additional healthcare support may be needed to adequately mitigate the impact of COVID-19 on men’s health. TC Hsieh, NC Edwards, SK Bhattacharyya, et al. The erectile dysfunction epidemic linked to COVID-19: a review of the scope and perspective of healthcare. Gender Med Rev 2021; XX: XXX-XXX.

PMID: 34732316 | PMC: PMC8450276 | DOI: 10.1016 / j.sxmr.2021.09.002